Neurotrauma Research Program (NRP)


http://www.nrp.org.au

NRP Publications

Full-length scientific papers that have arisen from NRP studies since 2007
(list updated in June 2010)

Reducing secondary degeneration, keeping cells alive (basic science)

  1. Fitzgerald M, Bartlett CA, Evill L, Rodger J, Harvey AR, Dunlop SA. (2009) Secondary degeneration of the optic nerve following partial transection: the benefits of lomerizine. Experimental Neurology 216, 219-230. (DOI information: 10.1016/j.expneurol.2008.11.026) Impact Factor = 3.9 [NCBI PubMed Entry]
  2. Fitzgerald M, Payne SC, Bartlett CA, Evill L, Harvey AR, Dunlop SA. (2009) Secondary retinal ganglion cell death and the neuroprotective effects of the calcium channel blocker, lomerizine. Invest Ophthalmol Vis Sci. November 2009, Vol. 50, No. 11,5456-5462 (Impact Factor = 3.528) [NCBI PubMed Entry]
  3. Selt M, Bartlett CA, Harvey AR, Dunlop SA, Fitzgerald M. (2009) Limited restoration of visual function after partial optic nerve injury; a time course study using the calcium channel blocker lomerizine. In press, Brain Research Bulletin E-pub 17/11/2009. doi:10.1016/j.brainresbull.2009.11.004 (IF 2.281) [NCBI PubMed Entry]
  4. Fitzgerald M*, Bartlett CA, Harvey AR, Dunlop SA*. (2009) Early events of secondary degeneration after partial optic nerve transection: an immunohistochemical study. In press, J. Neurotrauma E-pub 27/10/2009 *note equal contribution by these authors (IF 3.528) [NCBI PubMed Entry]

Neural Regeneration and Repair (basic science)

  1. Hu Y, Cui Q, Harvey AR. (2007) Interactive effects of C3, cyclic AMP and ciliary neurotrophic factor on adult retinal ganglion cell survival and axonal regeneration. Mol. Cell. Neurosci. 34 (2007) 88-98 [NCBI PubMed Entry]
  2. Vukovic J, Plant GW, Ruitenberg MJ, Harvey AR. (2007) Influence of adult Schwann cells and adult olfactory ensheathing glia on axon-target cell interactions in the CNS. Neuron Glia Biol - in press 14/11/07. No impact factor as yet - new journal (then cited as 0.937 in 2008) [NCBI PubMed Entry]
  3. Cui Q, Hodgetts SI, Hu Y, Luo J-M, Harvey AR. (2007) Strain-specific differences in the effects of cyclosporin-A and FK506 on the survival and regeneration of axotomized retinal ganglion cells in adult rats. Neuroscience, 146: 986-999. (2006 Impact Factor 3.43) [NCBI PubMed Entry]
  4. Hu Y, Arulpragasam A, Plant GW, Hendriks WTJ, Cui Q, Harvey AR. (2007) The importance of transgene and cell type on the regeneration of adult retinal ganglion cell axons within reconstituted bridging grafts. Exp. Neurol., 207: 314-328. (2006 Impact Factor 4.16) [NCBI PubMed Entry]
  5. Luo J-M, Zhi Y, Chen Q, Cen L-P, Zhang C-W, Zhang X-M, Lam DSC, Harvey AR, Pang CP, Cui Q. (2007) Influence of macrophages and lymphocytes on the survival and regeneration of injured retinal ganglion cells in rats from different autoimmune backgrounds. Eur. J. Neurosci., 26: 3475-3485. (2006 Impact Factor 3.72) [NCBI PubMed Entry]
  6. Mellough CB, Cui Q, Harvey AR. (2007) Engraftment of adult neural progenitor cells into neonatal and adult rat retinae selectively depleted of retinal ganglion cells. Restor. Neurol. Neurosci. 25: 177-190. (2006 Impact Factor 2.86) [NCBI PubMed Entry]
  7. Vukovic J, Ruitenberg MJ, Roet K, Fransen E, Arulpragasam A, Sasaki T, Verhaagen J, Harvey AR, Busfield S, Plant GW. (2008) The Glycoprotein fibulin-3 regulates morphology and motility of olfactory ensheathing glia in vitro. Glia. Mar;57(4):424-43. Impact Factor: 5.38 [NCBI PubMed Entry]
  8. Harvey AR, Hellstrom M, Rodger J. (2009) Gene therapy and transplantation in the retinofugal pathway. Prog. Brain Res., 175: 151-161. (IF 3.25) [NCBI PubMed Entry]
  9. Hellström M, Ruitenberg MJ, Pollett MA, Ehlert EME, Twisk J, Verhaagen J, Harvey AR. (2009) Cellular tropism and transduction properties of 7 adeno-associated viral vector serotypes in adult retina after vitreal injection. Gene Ther., 16: 521-532. (IF 4.49). [NCBI PubMed Entry]
  10. Lee J-P, Tsai DJ, Park KI, Harvey AR, Snyder EY. (2009) The dynamics of long-term transgene expression in engrafted neural stem cells. J Comp. Neurol., 515: 83-92. (IF 3.74) [NCBI PubMed Entry]
  11. Park KK, Hu Y, Muhling J, Pollett MA, Dallimore EJ, Turnley AM, Cui Q, Harvey AR. (2009) Cytokine-induced SOCS expression is inhibited by cAMP analogue: impact on regeneration of injured retina. Mol. Cell Neurosci., 41: 313-324. (IF 3.93) [NCBI PubMed Entry]
  12. Vukovic J, Marmostein LY, McLaughlin PJ, Sasaki T, Plant GW, Harvey AR, Ruitenberg MJ. (2009) Role of fibulin-3 in the developing and regenerating primary olfactory system. Matrix Biol., 28: 406-415. (IF 3.61) [NCBI PubMed Entry]

Guiding neural growth, restoring topography and connectivity (basic science)

  1. Haustead DJ, Lukehurst SS, Clutton G, Bartlett CA, Dunlop SA, Arrese CA, Sherrard RM, Rodger J. (2008) Functional topography and integration of the contralateral and ipsilateral retinocollicular projections of ephrin-A-/- mice. J. Neuroscience 28:7376 -7386. Impact Factor: 3.556 [NCBI PubMed Entry]
  2. Fitzgerald M, Buckley A, Lukehurst SS, Dunlop SA, Beazley LD, Rodger J. (2008) Neurite responses to ephrin-A5 modulated by BDNF: evidence for TrkB-EphA interactions. Biochem Biophys Res Commun. 374, 625-30. Impact Factor: 2.648 [NCBI PubMed Entry]
  3. Wilks TA, Rodger J, Harvey AR. (2010) A role for ephrin-As in maintaining topographic organisation in register across interconnected central visual pathways. Eur. J. Neurosci., Vol. 31, pp. 613-622 (IF 3.67) [NCBI PubMed Entry]
  4. Rodger J, Frost DO. (2009) Effects of trkB knockout on topography and ocular segregation of uncrossed retinal projections. Exp Brain Res. 195, 35-44. [NCBI PubMed Entry]
  5. Sherrard RM, Dixon KJ, Bakouche J, Rodger J, Lemaigre-Dubreuil Y, Mariani J. (2009) Differential expression of TrkB isoforms switches climbing fiber-Purkinje cell synaptogenesis to selective synapse elimination. Dev Neurobiol. 69: 647-662. Impact Factor: 7.49 [NCBI PubMed Entry]
  6. Migani P, Bartlett CA, Dunlop SA, Rodger J. (2009). Regional and cellular distribution of ephrin-B1 in adult mouse brain. Brain Research, 1247, 50-61. Impact Factor: 2.494 [NCBI PubMed Entry]
  7. Arnall S, Cheam LY, Smart C, Rengel A, Fitzgerald M, Thivierge JP, Rodger J. (2010) Abnormal strategies during visual discrimination reversal learning in ephrin-A2-/- mice. Behavioural Brain Research, doi:10.1016/j.bbr.2010.01.023. IF: 3.214 [NCBI PubMed Entry]

Driving plasticity; optimising functional recovery (clinical research)

  1. Thickbroom GW. (2007) REVIEW: Transcranial magnetic stimulation and synaptic plasticity: Experimental framework and human models. Experimental Brain Research 180(4): 583-593 (doi: 10.1007/s00221-007-0991-3) Impact Factor: 1.967 [NCBI PubMed Entry]
  2. Dunlop SA. (2008) Activity-dependent plasticity - implications for recovery from spinal cord injury. Trends in Neuroscience 31:410-418 [IF= 14.475] [NCBI PubMed Entry]
  3. Singer BJ, Dunne JW, Singer KP. (2008) The short term effect of cyclic passive stretching on plantarflexor resistive torque after acquired brain injury. Clinical Biomechanics; 23(9): 1178-82. Impact Factor: 2.000 [NCBI PubMed Entry]
  4. Move Again Program: Literature Search Part 1 'Exercise and spinal cord injury'; and Part 2 'Barriers to exercise for people with spinal cord injuries', R&A Lockwood Consultants, May 2008. Published on the websites of the Western Australian Institute for Medical Research and the Neurotrauma Research Program.
  5. Move Again Program: Information Scan, Exercise And Spinal Cord Injury (Activities and Resources in WA; Key International Centres, Researchers, and Resources), R&A Lockwood Consultants, May 2008. Published on the websites of the Western Australian Institute for Medical Research and the Neurotrauma Research Program.
  6. Cash RF, Benwell NM, Murray K, Mastaglia FL, Thickbroom GW. (2009) Neuromodulation by paired-pulse TMS at an I-wave interval facilitates multiple I-waves. Experimental Brain Research 193:1-7 (doi: 10.1007/s00221-008-1590-7) [NCBI PubMed Entry]
  7. Sacco P, Turner D, Rothwell JC, Thickbroom GW. (2009) Corticomotor responses to triple-pulse magnetic stimulation: Effects of interstimulus interval and stimulus intensity. Brain Stimulation 2(1):36-40. Impact Factor: none, new journal [NCBI PubMed Entry]
  8. Huang Y-Z, Sommer M, Thickbroom GW, Hamada M, Pascual-Leonne A, Paulus W, Classen J, Peterchev AV, Zangen A, Ugawa Y. (2009) Consensus: New methodologies for brain stimulation. Brain Stimulation 2(1):2-13. Impact Factor: none, new journal [NCBI PubMed Entry]
  9. Thickbroom GW, Mastaglia FL. (2009) Plasticity in neurological disorders and challenges for noninvasive brain stimulation. Journal of NeuroEngineering and Rehabilitation. 6:4 (doi: 10.1186/1743-0003-6-4). Impact Factor: 2.09 [NCBI PubMed Entry]
  10. Cash RHF, Ziemann U, Murray K, Thickbroom GW. (2009) Late cortical disinhibition in human motor cortex: A triple-pulse transcranial magnetic stimulation study. J Neurophysiol (November 18, 2009). doi:10.1152/jn.00782.2009 (IF: 3.648) [NCBI PubMed Entry]
  11. Nunn M, Knight M, Brayshaw J. (2009) Does the Cognitive Assessment of Minnesota accurately predict functional outcomes of patients with cognitive deficits following an acquired brain injury? Journal of Cognitive Rehab., Winter 2009, p6-14 (this project was funded by NRP in 2005-2006)

Book Chapters published by NRP-funded investigators from 2007 onwards
(list updated in June 2010)

  1. Dalton PD, Harvey AR, Oudega M, Plant GW. (2006) Tissue Engineering of the Nervous System, in The Tissue Engineering and Regenerative Medicine Textbook. (A Lindahl, P Thomsen, D Williams, J Hubbell, R Cancellah (Ed.) Landes)
  2. Lloyd DG, Besier TF, Winby CR, Buchanan TS. (2007) Neuromusculoskeletal modelling and simulation of tissue load in the lower extremities. Routledge Handbook of Biomechanics and Human Movement Science, Editors: Y Hong and R Bartlett, Taylor & Francis Books Ltd, Oxford, UK. P3-17.
  3. Harvey AR, Ehlert E, de Wit J, Drummond ES, Pollett MA, Ruitenberg MJ, Plant GW, Verhaagen J, Levelt C. (2008) Use of GFP to Analyze Morphology, Connectivity, and Function of Cells in the Central Nervous System. Human Press, Hicks (Ed) [NCBI PubMed Entry]
  4. Hodgetts SI, Plant GW, Harvey AR. (2009) Spinal cord injury: experimental animal models and relation to human therapy. In: The Spinal Cord: A Christopher and Dana Reeve Foundation Text and Atlas. C Watson, G Paxinos, G Kayalioglu, C Heise (Eds) Elsevier, pp 223-251.
  5. Watson CRR, Harvey AR. (2009) Brain projections to the spinal cord. In: The Spinal Cord: A Christopher and Dana Reeve Foundation Text and Atlas. C Watson, G Paxinos, G Kayalioglu, C Heise (Eds), Elsevier, pp 182-193.
  6. Harvey AR, Ehlert E, de Wit J, Drummond ES, Pollett MA, Ruitenberg MJ, Plant GW, Verhaagen J, Levelt C. (2009) Use of GFP to analyze morphology, connectivity, and function of cells in the central nervous system. In: Methods Mol. Biol., Viral Applications of Green Fluorescent Protein, R Hicks (Ed), 515: 63-95 (Figure from chapter used as front cover for book). [NCBI PubMed Entry]
  7. Harvey AR, Sakiyama-Elbert SE, Plant GW and Hodgetts S. (2009) Handbook of Clinical Neurology - Volume on Spinal Cord Trauma. 'Artificial scaffolds to promote spinal cord regeneration' (GWP 25%) (In Press)